Course disputée sur le circuit de Assen
| Position | Numéro | Pilote | Team | Temps | Tours | Points | Départ |
|---|---|---|---|---|---|---|---|
| 1 | 1 | Casey Stoner | Ducati Marlboro Team | 42'12.337 | 26 | 25 | 1 |
| 2 | 2 | Dani Pedrosa | Repsol Honda Team | 42'23.647 | 26 | 20 | 2 |
| 3 | 5 | Colin Edwards | Tech3 Yamaha | 42'29.462 | 26 | 16 | 6 |
| 4 | 69 | Nicky Hayden | Repsol Honda Team | 42'32.814 | 26 | 13 | 4 |
| 5 | 4 | Andrea Dovizioso | Jir Team Scot MotoGP | 42'39.683 | 26 | 11 | 11 |
| 6 | 48 | Jorge Lorenzo | Fiat Yamaha Team | 42'40.945 | 26 | 10 | 7 |
| 7 | 7 | Chris Vermeulen | Rizla Suzuki MotoGP | 42'44.667 | 26 | 9 | 8 |
| 8 | 56 | Shinya Nakano | San Carlo Honda Gresini | 42'47.229 | 26 | 8 | 9 |
| 9 | 52 | James Toseland | Tech3 Yamaha | 42'50.903 | 26 | 7 | 13 |
| 10 | 50 | Sylvain Guintoli | Alice Team | 42'51.154 | 26 | 6 | 10 |
| 11 | 46 | Valentino Rossi | Fiat Yamaha Team | 42'58.362 | 26 | 5 | 3 |
| 12 | 24 | Toni Elias | Alice Team | 43'00.550 | 26 | 4 | 14 |
| 13 | 33 | Marco Melandri | Ducati Marlboro Team | 43'11.931 | 26 | 3 | 17 |
| 14 | 13 | Anthony West | Kawasaki Racing Team | 11'41.383 | 19 | 0 | 16 |
| 15 | 14 | Randy De Puniet | LCR Honda MotoGP | 0 | 0 | 5 | |
| 16 | 15 | Alex De Angelis | San Carlo Honda Gresini | 0 | 0 | 12 |