Course disputée sur le circuit de Laguna-seca
| Position | Numéro | Pilote | Team | Temps | Tours | Points | Départ |
|---|---|---|---|---|---|---|---|
| 1 | 46 | Valentino Rossi | Fiat Yamaha Team | 15:31:51 | 32 | 25 | 2 |
| 2 | 1 | Casey Stoner | Ducati Marlboro Team | 19:08:32 | 32 | 20 | 1 |
| 3 | 7 | Chris Vermeulen | Rizla Suzuki MotoGP | 22:55:20 | 32 | 16 | 3 |
| 4 | 4 | Andrea Dovizioso | Jir Team Scot MotoGP | 01:13:32 | 32 | 13 | 14 |
| 5 | 69 | Nicky Hayden | Repsol Honda Team | 01:26:14 | 32 | 11 | 9 |
| 6 | 14 | Randy De Puniet | LCR Honda MotoGP | 01:59:39 | 32 | 10 | 8 |
| 7 | 24 | Toni Elias | Alice Team | 03:05:40 | 32 | 9 | 16 |
| 8 | 11 | Ben Spies | Rizla Suzuki MotoGP | 03:10:38 | 32 | 8 | 12 |
| 9 | 52 | James Toseland | Tech3 Yamaha | 03:28:50 | 32 | 7 | 17 |
| 10 | 56 | Shinya Nakano | San Carlo Honda Gresini | 03:51:42 | 32 | 6 | 6 |
| 11 | 12 | Jamie Hacking | Kawasaki Racing Team | 04:22:49 | 32 | 5 | 11 |
| 12 | 50 | Sylvain Guintoli | Alice Team | 06:53:04 | 32 | 4 | 5 |
| 13 | 15 | Alex De Angelis | San Carlo Honda Gresini | 06:57:12 | 32 | 3 | 13 |
| 14 | 5 | Colin Edwards | Tech3 Yamaha | 08:51:31 | 32 | 2 | 15 |
| 15 | 65 | Loris Capirossi | Rizla Suzuki MotoGP | 10:28:38 | 32 | 1 | 7 |
| 16 | 33 | Marco Melandri | Ducati Marlboro Team | 11:14:33 | 32 | 0 | 4 |
| 17 | 13 | Anthony West | Kawasaki Racing Team | 00:01:12 | 31 | 0 | 18 |
| 18 | 48 | Jorge Lorenzo | Fiat Yamaha Team | 01:00:00 | 32 | 0 | 10 |