Course disputée sur le circuit de Barcelona Catalunya
| Position | Numéro | Pilote | Team | Temps | Tours | Points | Départ |
|---|---|---|---|---|---|---|---|
| 1 | 99 | Jorge Lorenzo | Fiat Yamaha Team | 04:00:05 | 25 | 25 | 1 |
| 2 | 26 | Dani Pedrosa | Repsol Honda Team | 05:19:19 | 25 | 20 | 4 |
| 3 | 27 | Casey Stoner | Ducati Marlboro Team | 05:22:41 | 25 | 16 | 2 |
| 4 | 14 | Randy De Puniet | LCR Honda MotoGP | 09:01:02 | 25 | 13 | 3 |
| 5 | 19 | Alvaro Bautista | Rizla Suzuki MotoGP | 09:56:06 | 25 | 11 | 9 |
| 6 | 11 | Ben Spies | Tech3 Yamaha | 09:58:28 | 25 | 10 | 5 |
| 7 | 65 | Loris Capirossi | Rizla Suzuki MotoGP | 10:43:06 | 25 | 9 | 7 |
| 8 | 69 | Nicky Hayden | Ducati Marlboro Team | 11:45:46 | 25 | 8 | 11 |
| 9 | 33 | Marco Melandri | San Carlo Honda Gresini | 11:47:31 | 25 | 7 | 14 |
| 10 | 40 | Hector Barbera | Paginas Amarillas Aspar | 13:00:44 | 25 | 6 | 13 |
| 11 | 5 | Colin Edwards | Tech3 Yamaha | 14:40:11 | 25 | 5 | 10 |
| 12 | 36 | Mika Kallio | Pramac Racing | 20:11:02 | 25 | 4 | 15 |
| 13 | 64 | Kousuke Akiyoshi | Interwetten Honda MotoGP | 23:15:53 | 25 | 3 | 16 |
| 14 | 4 | Andrea Dovizioso | Repsol Honda Team | 05:40:07 | 25 | 2 | 6 |
| 15 | 8 | Wataru Yoshikawa | Fiat Yamaha Team | 06:27:22 | 25 | 1 | 17 |
| 16 | 58 | Marco Simoncelli | San Carlo Honda Gresini | 18:59:59 | 13 | 0 | 8 |
| 17 | 41 | Aleix Espargaro | Pramac Racing | 04:02:31 | 5 | 0 | 12 |