Course disputée sur le circuit de Assen
| Position | Numéro | Pilote | Team | Temps | Tours | Points | Départ |
|---|---|---|---|---|---|---|---|
| 1 | 11 | Ben Spies | Yamaha Factory Racing | 00:44:19 | 26 | 25 | 2 |
| 2 | 27 | Casey Stoner | Repsol Honda Team | 02:52:36 | 26 | 20 | 3 |
| 3 | 4 | Andrea Dovizioso | Repsol Honda Team | 08:22:45 | 26 | 16 | 5 |
| 4 | 46 | Valentino Rossi | Ducati Team | 09:15:43 | 26 | 13 | 11 |
| 5 | 69 | Nicky Hayden | Ducati Team | 12:43:51 | 26 | 11 | 9 |
| 6 | 1 | Jorge Lorenzo | Yamaha Factory Racing | 13:06:35 | 26 | 10 | 4 |
| 7 | 5 | Colin Edwards | Monster Yamaha Tech 3 | 19:39:31 | 26 | 9 | 8 |
| 8 | 7 | Hiroshi Aoyama | San Carlo Honda Gresini | 20:23:32 | 26 | 8 | 12 |
| 9 | 58 | Marco Simoncelli | San Carlo Honda Gresini | 00:19:44 | 26 | 7 | 1 |
| 10 | 24 | Toni Elias | LCR Honda MotoGP | 00:41:15 | 26 | 6 | 15 |
| 11 | 19 | Alvaro Bautista | Rizla Suzuki MotoGP | 04:05:25 | 26 | 5 | 14 |
| 12 | 8 | Hector Barbera | Mapfre Aspar Team MotoGP | 08:03:37 | 25 | 4 | 13 |
| 13 | 64 | Kousuke Akiyoshi | San Carlo Honda Gresini | 21:13:57 | 25 | 3 | 16 |
| 14 | 35 | Cal Crutchlow | Monster Yamaha Tech 3 | 23:49:15 | 24 | 2 | 6 |
| 15 | 14 | Randy De Puniet | Pramac Racing Team | 08:14:54 | 1 | 0 | 10 |
| 16 | 17 | Karel Abraham | Cardion AB Motoracing | 01:00:00 | 0 | 0 | 7 |