Course disputée sur le circuit de Sepang International Circuit
| Position | Numéro | Pilote | Team | Temps | Tours | Points | Départ |
|---|---|---|---|---|---|---|---|
| 1 | 46 | Valentino Rossi | Fiat Yamaha Team | 23:20:07 | 21 | 25 | 2 |
| 2 | 2 | Dani Pedrosa | Repsol Honda Team | 00:26:55 | 21 | 20 | 1 |
| 3 | 4 | Andrea Dovizioso | Jir Team Scot MotoGP | 01:42:23 | 21 | 16 | 6 |
| 4 | 69 | Nicky Hayden | Repsol Honda Team | 01:47:45 | 21 | 13 | 4 |
| 5 | 56 | Shinya Nakano | San Carlo Honda Gresini | 02:16:30 | 21 | 11 | 15 |
| 6 | 1 | Casey Stoner | Ducati Marlboro Team | 03:07:27 | 21 | 10 | 7 |
| 7 | 65 | Loris Capirossi | Rizla Suzuki MotoGP | 03:45:43 | 21 | 9 | 8 |
| 8 | 5 | Colin Edwards | Tech3 Yamaha | 04:33:29 | 21 | 8 | 5 |
| 9 | 7 | Chris Vermeulen | Rizla Suzuki MotoGP | 05:46:21 | 21 | 7 | 11 |
| 10 | 14 | Randy De Puniet | LCR Honda MotoGP | 06:25:23 | 21 | 6 | 9 |
| 11 | 21 | John Hopkins | Kawasaki Racing Team | 07:00:16 | 21 | 5 | 10 |
| 12 | 13 | Anthony West | Kawasaki Racing Team | 10:50:06 | 21 | 4 | 13 |
| 13 | 50 | Sylvain Guintoli | Alice Team | 12:00:24 | 21 | 3 | 16 |
| 14 | 15 | Alex De Angelis | San Carlo Honda Gresini | 12:56:50 | 21 | 2 | 17 |
| 15 | 24 | Toni Elias | Alice Team | 15:45:46 | 21 | 1 | 19 |
| 16 | 33 | Marco Melandri | Ducati Marlboro Team | 16:55:35 | 21 | 0 | 14 |
| 17 | 9 | Nobuatsu Aoki | Rizla Suzuki MotoGP | 05:26:10 | 21 | 0 | 18 |
| 18 | 48 | Jorge Lorenzo | Fiat Yamaha Team | 20:22:37 | 9 | 0 | 3 |
| 19 | 52 | James Toseland | Tech3 Yamaha | 00:58:42 | 19 | 0 | 12 |