Course disputée sur le circuit de Le Mans
| Position | Numéro | Pilote | Team | Temps | Tours | Points | Départ |
|---|---|---|---|---|---|---|---|
| 1 | 99 | Jorge Lorenzo | Fiat Yamaha Team | 22:25:14 | 28 | 25 | 2 |
| 2 | 46 | Valentino Rossi | Fiat Yamaha Team | 23:59:46 | 28 | 20 | 1 |
| 3 | 4 | Andrea Dovizioso | Repsol Honda Team | 00:36:26 | 28 | 16 | 7 |
| 4 | 69 | Nicky Hayden | Ducati Marlboro Team | 01:01:00 | 28 | 13 | 5 |
| 5 | 26 | Dani Pedrosa | Repsol Honda Team | 01:55:27 | 28 | 11 | 3 |
| 6 | 33 | Marco Melandri | San Carlo Honda Gresini | 04:30:32 | 28 | 10 | 11 |
| 7 | 14 | Randy De Puniet | LCR Honda MotoGP | 06:33:22 | 28 | 9 | 6 |
| 8 | 40 | Hector Barbera | Paginas Amarillas Aspar | 07:37:22 | 28 | 8 | 15 |
| 9 | 41 | Aleix Espargaro | Pramac Racing | 07:43:27 | 28 | 7 | 10 |
| 10 | 58 | Marco Simoncelli | San Carlo Honda Gresini | 07:48:39 | 28 | 6 | 13 |
| 11 | 7 | Hiroshi Aoyama | Interwetten Honda MotoGP | 07:57:40 | 28 | 5 | 14 |
| 12 | 5 | Colin Edwards | Tech3 Yamaha | 08:43:57 | 28 | 4 | 8 |
| 13 | 36 | Mika Kallio | Pramac Racing | 13:42:55 | 28 | 3 | 16 |
| 14 | 11 | Ben Spies | Tech3 Yamaha | 20:08:04 | 6 | 0 | 12 |
| 15 | 65 | Loris Capirossi | Rizla Suzuki MotoGP | 19:15:22 | 6 | 0 | 9 |
| 16 | 27 | Casey Stoner | Ducati Marlboro Team | 08:10:38 | 2 | 0 | 4 |