Course disputée sur le circuit de Le Mans
| Position | Numéro | Pilote | Team | Temps | Tours | Points | Départ |
|---|---|---|---|---|---|---|---|
| 1 | 99 | Jorge Lorenzo | Fiat Yamaha Team | 44'29.114 | 28 | 25 | 2 |
| 2 | 46 | Valentino Rossi | Fiat Yamaha Team | 44'34.786 | 28 | 20 | 1 |
| 3 | 4 | Andrea Dovizioso | Repsol Honda Team | 44'36.986 | 28 | 16 | 7 |
| 4 | 69 | Nicky Hayden | Ducati Marlboro Team | 44'38.460 | 28 | 13 | 5 |
| 5 | 26 | Dani Pedrosa | Repsol Honda Team | 44'41.727 | 28 | 11 | 3 |
| 6 | 33 | Marco Melandri | San Carlo Honda Gresini | 44'51.032 | 28 | 10 | 11 |
| 7 | 14 | Randy De Puniet | LCR Honda MotoGP | 44'58.402 | 28 | 9 | 6 |
| 8 | 40 | Hector Barbera | Paginas Amarillas Aspar | 45'02.242 | 28 | 8 | 15 |
| 9 | 41 | Aleix Espargaro | Pramac Racing | 45'02.607 | 28 | 7 | 10 |
| 10 | 58 | Marco Simoncelli | San Carlo Honda Gresini | 45'02.919 | 28 | 6 | 13 |
| 11 | 7 | Hiroshi Aoyama | Interwetten Honda MotoGP | 45'03.460 | 28 | 5 | 14 |
| 12 | 5 | Colin Edwards | Tech3 Yamaha | 45'06.237 | 28 | 4 | 8 |
| 13 | 36 | Mika Kallio | Pramac Racing | 45'24.175 | 28 | 3 | 16 |
| 14 | 11 | Ben Spies | Tech3 Yamaha | 9'47.284 | 6 | 0 | 12 |
| 15 | 65 | Loris Capirossi | Rizla Suzuki MotoGP | 9'44.122 | 6 | 0 | 9 |
| 16 | 27 | Casey Stoner | Ducati Marlboro Team | 3'18.638 | 2 | 0 | 4 |