Course disputée sur le circuit de Estoril
| Position | Numéro | Pilote | Team | Temps | Tours | Points | Départ |
|---|---|---|---|---|---|---|---|
| 1 | 26 | Dani Pedrosa | Repsol Honda Team | 45'51.483 | 28 | 25 | 3 |
| 2 | 1 | Jorge Lorenzo | Yamaha Factory Racing | 45'54.534 | 28 | 20 | 1 |
| 3 | 27 | Casey Stoner | Repsol Honda Team | 45'59.141 | 28 | 16 | 4 |
| 4 | 4 | Andrea Dovizioso | Repsol Honda Team | 46'08.013 | 28 | 13 | 6 |
| 5 | 46 | Valentino Rossi | Ducati Team | 46'08.038 | 28 | 11 | 9 |
| 6 | 5 | Colin Edwards | Monster Yamaha Tech 3 | 46'24.058 | 28 | 10 | 7 |
| 7 | 7 | Hiroshi Aoyama | San Carlo Honda Gresini | 46'30.232 | 28 | 9 | 11 |
| 8 | 35 | Cal Crutchlow | Monster Yamaha Tech 3 | 46'32.395 | 28 | 8 | 8 |
| 9 | 69 | Nicky Hayden | Ducati Team | 46'46.370 | 28 | 7 | 13 |
| 10 | 14 | Randy De Puniet | Pramac Racing Team | 46'51.180 | 28 | 6 | 16 |
| 11 | 24 | Toni Elias | LCR Honda MotoGP | 46'51.857 | 28 | 5 | 17 |
| 12 | 65 | Loris Capirossi | Pramac Racing Team | 46'53.276 | 28 | 4 | 14 |
| 13 | 19 | Alvaro Bautista | Rizla Suzuki MotoGP | 47'15.853 | 28 | 3 | 15 |
| 14 | 11 | Ben Spies | Yamaha Factory Racing | 20'06.256 | 12 | 0 | 5 |
| 15 | 17 | Karel Abraham | Cardion AB Motoracing | 1'50.239 | 1 | 0 | 12 |
| 16 | 58 | Marco Simoncelli | San Carlo Honda Gresini | 0 | 0 | 2 | |
| 17 | 8 | Hector Barbera | Mapfre Aspar Team MotoGP | 0 | 0 | 10 |