Course disputée sur le circuit de Jerez de la Frontera
| Position | Numéro | Pilote | Team | Temps | Tours | Points | Départ |
|---|---|---|---|---|---|---|---|
| 1 | 2 | Dani Pedrosa | Repsol Honda Team | 16:45:21 | 27 | 25 | 2 |
| 2 | 46 | Valentino Rossi | Fiat Yamaha Team | 17:33:24 | 27 | 20 | 5 |
| 3 | 48 | Jorge Lorenzo | Fiat Yamaha Team | 17:57:40 | 27 | 16 | 1 |
| 4 | 69 | Nicky Hayden | Repsol Honda Team | 19:34:23 | 27 | 13 | 4 |
| 5 | 65 | Loris Capirossi | Rizla Suzuki MotoGP | 00:24:05 | 27 | 11 | 10 |
| 6 | 52 | James Toseland | Tech3 Yamaha | 00:28:49 | 27 | 10 | 8 |
| 7 | 21 | John Hopkins | Kawasaki Racing Team | 00:36:57 | 27 | 9 | 9 |
| 8 | 4 | Andrea Dovizioso | Jir Team Scot MotoGP | 00:39:30 | 27 | 8 | 13 |
| 9 | 56 | Shinya Nakano | San Carlo Honda Gresini | 01:48:10 | 27 | 7 | 11 |
| 10 | 7 | Chris Vermeulen | Rizla Suzuki MotoGP | 02:30:12 | 27 | 6 | 12 |
| 11 | 1 | Casey Stoner | Ducati Marlboro Team | 04:29:04 | 27 | 5 | 7 |
| 12 | 33 | Marco Melandri | Ducati Marlboro Team | 05:06:59 | 27 | 4 | 18 |
| 13 | 13 | Anthony West | Kawasaki Racing Team | 05:28:48 | 27 | 3 | 15 |
| 14 | 15 | Alex De Angelis | San Carlo Honda Gresini | 05:29:52 | 27 | 2 | 14 |
| 15 | 24 | Toni Elias | Alice Team | 12:04:39 | 27 | 1 | 16 |
| 16 | 50 | Sylvain Guintoli | Alice Team | 13:26:03 | 27 | 0 | 17 |
| 17 | 5 | Colin Edwards | Tech3 Yamaha | 09:52:28 | 22 | 0 | 3 |
| 18 | 14 | Randy De Puniet | LCR Honda MotoGP | 11:38:47 | 25 | 0 | 6 |