Course disputée sur le circuit de Assen
| Position | Numéro | Pilote | Team | Temps | Tours | Points | Départ |
|---|---|---|---|---|---|---|---|
| 1 | 46 | Valentino Rossi | Fiat Yamaha Team | 15:19:09 | 26 | 25 | 11 |
| 2 | 27 | Casey Stoner | Ducati Marlboro Team | 15:50:58 | 26 | 20 | 2 |
| 3 | 1 | Nicky Hayden | Repsol Honda Team | 17:00:26 | 26 | 16 | 13 |
| 4 | 26 | Dani Pedrosa | Repsol Honda Team | 18:13:34 | 26 | 13 | 9 |
| 5 | 21 | John Hopkins | Rizla Suzuki MotoGP | 18:58:07 | 26 | 11 | 5 |
| 6 | 5 | Colin Edwards | Fiat Yamaha Team | 19:31:28 | 26 | 10 | 6 |
| 7 | 4 | Alex Barros | Pramac d\'Antin | 01:20:24 | 26 | 9 | 12 |
| 8 | 66 | Alexander Hofmann | Pramac d\'Antin | 02:55:17 | 26 | 8 | 8 |
| 9 | 13 | Anthony West | Kawasaki Racing Team | 03:25:54 | 26 | 7 | 7 |
| 10 | 33 | Marco Melandri | San Carlo Honda Gresini | 03:29:05 | 26 | 6 | 4 |
| 11 | 7 | Carlos Checa | LCR Honda MotoGP | 03:29:35 | 26 | 5 | 16 |
| 12 | 56 | Shinya Nakano | Konica Minolta Honda | 04:37:25 | 26 | 4 | 15 |
| 13 | 6 | Makoto Tamada | Tech3 Yamaha | 06:20:17 | 26 | 3 | 18 |
| 14 | 50 | Sylvain Guintoli | Tech3 Yamaha | 07:21:07 | 26 | 2 | 17 |
| 15 | 80 | Kurtis Roberts | Team Roberts | 15:56:26 | 26 | 1 | 14 |
| 16 | 71 | Chris Vermeulen | Rizla Suzuki MotoGP | 17:39:17 | 26 | 0 | 1 |
| 17 | 65 | Loris Capirossi | Ducati Marlboro Team | 01:08:37 | 9 | 0 | 10 |
| 18 | 14 | Randy De Puniet | Kawasaki Racing Team | 17:01:47 | 15 | 0 | 3 |