Course disputée sur le circuit de Sepang International Circuit
| Position | Numéro | Pilote | Team | Temps | Tours | Points | Départ |
|---|---|---|---|---|---|---|---|
| 1 | 27 | Casey Stoner | Ducati Marlboro Team | 23:13:54 | 21 | 25 | 4 |
| 2 | 3 | Dani Pedrosa | Repsol Honda Team | 03:18:20 | 21 | 20 | 3 |
| 3 | 46 | Valentino Rossi | Fiat Yamaha Team | 04:36:59 | 21 | 16 | 1 |
| 4 | 99 | Jorge Lorenzo | Fiat Yamaha Team | 06:24:44 | 21 | 13 | 2 |
| 5 | 69 | Nicky Hayden | Ducati Marlboro Team | 09:58:59 | 21 | 11 | 7 |
| 6 | 7 | Chris Vermeulen | Rizla Suzuki MotoGP | 10:38:15 | 21 | 10 | 14 |
| 7 | 24 | Toni Elias | San Carlo Honda Gresini | 12:43:09 | 21 | 9 | 6 |
| 8 | 33 | Marco Melandri | Kawasaki Racing Team | 14:39:51 | 21 | 8 | 15 |
| 9 | 65 | Loris Capirossi | Rizla Suzuki MotoGP | 15:58:57 | 21 | 7 | 5 |
| 10 | 36 | Mika Kallio | Pramac Racing | 16:01:14 | 21 | 6 | 12 |
| 11 | 44 | Aleix Espargaro | Pramac d\'Antin | 16:21:29 | 21 | 5 | 13 |
| 12 | 15 | Alex De Angelis | San Carlo Honda Gresini | 16:24:41 | 21 | 4 | 10 |
| 13 | 5 | Colin Edwards | Tech3 Yamaha | 18:53:32 | 21 | 3 | 9 |
| 14 | 41 | Gabor Talmacsi | Scot Racing Team MotoGP | 20:18:05 | 21 | 2 | 17 |
| 15 | 52 | James Toseland | Tech3 Yamaha | 05:58:26 | 21 | 1 | 16 |
| 16 | 4 | Andrea Dovizioso | Repsol Honda Team | 06:08:41 | 14 | 0 | 11 |
| 17 | 14 | Randy De Puniet | LCR Honda MotoGP | 18:18:38 | 1 | 0 | 8 |