Course disputée sur le circuit de Barcelona Catalunya
| Position | Numéro | Pilote | Team | Temps | Tours | Points | Départ |
|---|---|---|---|---|---|---|---|
| 1 | 46 | Valentino Rossi | Fiat Yamaha Team | 00:58:17 | 25 | 25 | 2 |
| 2 | 99 | Jorge Lorenzo | Fiat Yamaha Team | 00:59:52 | 25 | 20 | 1 |
| 3 | 27 | Casey Stoner | Ducati Marlboro Team | 03:26:21 | 25 | 16 | 3 |
| 4 | 4 | Andrea Dovizioso | Repsol Honda Team | 03:27:13 | 25 | 13 | 4 |
| 5 | 65 | Loris Capirossi | Rizla Suzuki MotoGP | 06:28:48 | 25 | 11 | 11 |
| 6 | 3 | Dani Pedrosa | Repsol Honda Team | 07:07:59 | 25 | 10 | 8 |
| 7 | 5 | Colin Edwards | Tech3 Yamaha | 07:30:44 | 25 | 9 | 6 |
| 8 | 14 | Randy De Puniet | LCR Honda MotoGP | 07:59:22 | 25 | 8 | 7 |
| 9 | 36 | Mika Kallio | Pramac Racing | 09:48:14 | 25 | 7 | 10 |
| 10 | 69 | Nicky Hayden | Ducati Marlboro Team | 10:18:10 | 25 | 6 | 13 |
| 11 | 7 | Chris Vermeulen | Rizla Suzuki MotoGP | 11:09:40 | 25 | 5 | 12 |
| 12 | 15 | Alex De Angelis | San Carlo Honda Gresini | 11:12:51 | 25 | 4 | 14 |
| 13 | 52 | James Toseland | Tech3 Yamaha | 11:55:30 | 25 | 3 | 9 |
| 14 | 33 | Marco Melandri | Kawasaki Racing Team | 13:24:45 | 25 | 2 | 17 |
| 15 | 59 | Sete Gibernau | Grupo Franciscio Hermando | 13:57:31 | 25 | 1 | 15 |
| 16 | 88 | Niccolo Canepa | Pramac Racing | 16:29:30 | 25 | 0 | 18 |
| 17 | 41 | Gabor Talmacsi | Scot Racing Team MotoGP | 01:18:57 | 25 | 0 | 19 |
| 18 | 24 | Toni Elias | San Carlo Honda Gresini | 23:33:34 | 16 | 0 | 5 |
| 19 | 72 | Yuki Takahashi | Scot Racing Team MotoGP | 01:00:00 | 0 | 0 | 16 |