Course disputée sur le circuit de Mugello
| Position | Numéro | Pilote | Team | Temps | Tours | Points | Départ |
|---|---|---|---|---|---|---|---|
| 1 | 93 | Marc Marquez | Repsol Honda Team | 22:57:34 | 23 | 25 | 1 |
| 2 | 99 | Jorge Lorenzo | Yamaha Factory Racing | 22:59:35 | 23 | 20 | 3 |
| 3 | 46 | Valentino Rossi | Yamaha Factory Racing | 23:42:22 | 23 | 16 | 10 |
| 4 | 26 | Dani Pedrosa | Repsol Honda Team | 02:51:40 | 23 | 13 | 4 |
| 5 | 44 | Pol Espargaro | Monster Yamaha Tech 3 | 03:17:37 | 23 | 11 | 5 |
| 6 | 4 | Andrea Dovizioso | Ducati Team | 03:41:36 | 23 | 10 | 8 |
| 7 | 29 | Andrea Iannone | Pramac Racing | 03:43:03 | 23 | 9 | 2 |
| 8 | 19 | Alvaro Bautista | Go&fun Honda Gresini | 06:34:21 | 23 | 8 | 11 |
| 9 | 41 | Aleix Espargaro | NGM Mobile Forward Racing | 10:35:40 | 23 | 7 | 12 |
| 10 | 68 | Yonny Hernandez | Pramac Racing | 11:31:06 | 23 | 6 | 13 |
| 11 | 51 | Michele Pirro | Ducati Team | 11:34:47 | 23 | 5 | 15 |
| 12 | 17 | Karel Abraham | Cardion AB Motoracing | 11:41:25 | 23 | 4 | 16 |
| 13 | 45 | Scott Redding | Go&fun Honda Gresini | 11:41:33 | 23 | 3 | 14 |
| 14 | 7 | Hiroshi Aoyama | Power Electronics Aspar | 11:58:08 | 23 | 2 | 17 |
| 15 | 5 | Colin Edwards | NGM Mobile Forward Racing | 18:16:48 | 23 | 1 | 18 |
| 16 | 70 | Michael Laverty | Paul Bird Racing (CRT) | 20:34:03 | 23 | 0 | 20 |
| 17 | 23 | Broc Parkes | Paul Bird Racing (CRT) | 01:21:25 | 23 | 0 | 22 |
| 18 | 63 | Mike Di Meglio | Avintia Blusens | 02:02:35 | 23 | 0 | 21 |
| 19 | 8 | Hector Barbera | Avintia Blusens | 05:31:25 | 7 | 0 | 19 |
| 20 | 84 | Michel Fabrizio | Ioda Racing Project | 01:46:37 | 6 | 0 | 23 |
| 21 | 6 | Stefan Bradl | LCR Honda MotoGP | 22:15:29 | 3 | 0 | 9 |
| 22 | 35 | Cal Crutchlow | Ducati Team | 22:00:26 | 3 | 0 | 6 |
| 23 | 38 | Bradley Smith | Monster Yamaha Tech 3 | 15:45:41 | 2 | 0 | 7 |